Key result
Children after successful repair of aortic coarctation had significantly higher systolic mitral annulus motion velocity (6.92 vs 6.45 cm/s) and left ventricular strain than healthy controls.
Why the study?
Does left ventricular systolic function assessed by tissue Doppler imaging differ in children after successful repair of aortic coarctation compared to healthy controls?
Observational (n=66)
Does left ventricular systolic function assessed by tissue Doppler imaging differ in children after successful repair of aortic coarctation compared to healthy controls?
Absolute Event Rate: 6.92% vs 6.45%
Children after surgical repair of aortic coarctation exhibit increased preserved left ventricular systolic performance on tissue Doppler imaging despite normalization of afterload.
Suggests preserved LV systolic function after repair; hypothesis-generating and requires longitudinal studies before clinical relevance.
UNLABELLED: SUMMARY AIM: Assessment of left ventricular systolic function in children after the successful repair of aortic coarctation using tissue Doppler imaging (TDI). METHODS: The study group consisted of 32 patients (mean age 12.0 +/- 4.2 years) after the aortic coarctation repair. The TDI parameters and the conventional echocardiographic endocardial and midwall indices of the left ventricular systolic function were analysed and compared with the results obtained from 34 healthy children. RESULTS: The systolic mitral annulus motion velocity, systolic myocardial velocity of the medial segment of the left ventricular septal wall, left ventricular strain and Strain Rate (SR) in the study group were significantly higher than in the control group, respectively: 6.92 +/- 0.75 cm s(-1) versus 6.45 +/- 0.83 cm s(-1); 5.82 +/- 1.03 cm s(-1) versus 5.08 +/- 1.11 cm s(-1); -28.67 +/- 6.04% versus -22.53 +/- 6.44% and -3.20 +/- 0.76 s(-1) versus -2.39 +/- 0.49 s(-1). Except midwall shortening fraction the conventional endocardial and midwall echocardiographic indices in the study group were significantly higher in comparison to the healthy controls. The left ventricular systolic meridional fibre stress and end-systolic circumferential wall stress did not differ between the examined groups. There were no differences of the TDI or conventional parameters between hypertensive and normotensive patients. CONCLUSIONS: Left ventricular systolic performance in children after the surgical repair of aortic coarctation reveals tendency to rise in late follow-up despite a satisfactory result after surgery. Higher systolic strain and SR in children treated due to coarctation of the aorta may suggest the increased preserved left ventricular performance despite normalization of afterload.
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Floriańczyk et al. (2009) conducted an observational in Aortic coarctation (n=66). Successful repair of aortic coarctation vs. Healthy children was evaluated on Systolic mitral annulus motion velocity. Children after successful repair of aortic coarctation had significantly higher systolic mitral annulus motion velocity (6.92 vs 6.45 cm/s) and left ventricular strain than healthy controls.
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