Key result
WFNS grade determined postresuscitation was strongly associated with poor functional outcome (OR 3.43, p<0.0001) and had a higher predictive value (AUC 0.90) than admission or nadir grades.
Why the study?
At which time point is clinical assessment using the WFNS grading scale and GCS most predictive of poor functional outcome in patients with aneurysmal subarachnoid hemorrhage?
Cohort (n=186)
No
At which time point is clinical assessment using the WFNS grading scale and GCS most predictive of poor functional outcome in patients with aneurysmal subarachnoid hemorrhage?
Odds Ratio: 3.43
p-value: p=<0.0001
In patients with aneurysmal subarachnoid hemorrhage, clinical grading using the WFNS scale is most predictive of 6-month functional outcome when assessed after neurological resuscitation rather than at initial presentation or nadir.
Authors
No takes yet. Share an insight, caveat, or question.
Postresuscitation WFNS assessment may refine prognostication in aSAH; supports timing-specific evaluation but leaves open prospective validation before practice change.
Giraldo et al. (2012) conducted a cohort in Aneurysmal subarachnoid hemorrhage (SAH) (n=186). WFNS grade postresuscitation vs. WFNS grade assessed upon admission or at nadir was evaluated on Poor functional outcome (Glasgow Outcome Scale score of 1-3 at 6 months) (OR 3.43, p=<0.0001). WFNS grade determined postresuscitation was strongly associated with poor functional outcome (OR 3.43, p<0.0001) and had a higher predictive value (AUC 0.90) than admission or nadir grades.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: