Why the study?
Does capillary blood gas analysis accurately reflect arterial blood gas analysis for guiding appropriate therapy in patients with diabetic ketoacidosis?
Does capillary blood gas analysis accurately reflect arterial blood gas analysis for guiding appropriate therapy in patients with diabetic ketoacidosis?
There is insufficient evidence to recommend the use of capillary blood as an alternative to arterial puncture for assessing acid-base status in patients with diabetic ketoacidosis in the emergency setting.
Should not yet replace arterial sampling for DKA acid-base assessment; leaves open need for prospective validation.
A short cut review was carried out to establish whether capillary blood rather than arterial blood can be used to assess acid base status in patients with diabetic ketoacidosis. A total of 25 papers were found using the reported searches, of which one presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of this best paper are presented in table 1. It is concluded that while the correlations in the small study found were good, there is insufficient evidence to recommend adoption of this practice in the emergency setting.
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Clarke et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: