Key result
Electrodiagnostic studies, including the long exercise test, successfully differentiated secondary hypokalemic paralysis from primary hypokalemic periodic paralysis in two male patients.
Why the study?
Routine electrodiagnostic examinations can be normal between attacks of hypokalemic paralysis, potentially interfering with the diagnosis.
Case Report (n=2)
No
A proper combination of routine electrodiagnostic studies and special techniques like the long exercise test is needed to diagnose hypokalemic paralysis and exclude other causes.
Intra-attack electrodiagnostics may aid hypokalemic paralysis diagnosis; leaves open validation in larger prospective cohorts.
Hypokalemic paralysis is a cause of acute paralysis that can be classified as primary (familial) or secondary according to its etiology. Routine electrodiagnostic examinations can be normal between attacks, potentially interfering with the diagnosis. We report two cases of hypokalemic paralysis with different etiologies. The first case involved secondary hypokalemic paralysis due to pharmacologic potassium shift, which was diagnosed by an electrodiagnostic study within the symptomatic period. The second case provides information on the diagnostic approach to primary hypokalemic periodic paralysis during the inter-attack period, as the diagnosis was made using the long exercise test. This case report highlights the need for a proper combination of routine electrodiagnostic studies and special techniques, such as the long exercise test, in patients suspected of hypokalemic paralysis to evaluate the disease state and exclude other possible causes of paralysis.
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Jeong et al. (2021) conducted a case report in Hypokalemic paralysis (n=2). Electrodiagnostic study including long exercise test was evaluated on Diagnostic confirmation of hypokalemic paralysis etiology. Electrodiagnostic studies, including the long exercise test, successfully differentiated secondary hypokalemic paralysis from primary hypokalemic periodic paralysis in two male patients.
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