What is the clinical evidence from this study?

Study design: Observational. Population: Aortic stenosis and/or regurgitation (n=11). Intervention: Modified Ross procedure using a synthetic valved conduit. Primary outcome: In-hospital or late mortality.

What question did this study set out to answer?

To evaluate early valvular and right ventricular function in patients undergoing a modified Ross procedure with a synthetic valved conduit for right ventricular outflow tract reconstruction.

September 29, 2004European Journal of Cardio-Thoracic SurgeryOpen Access

Modified Ross procedure using a conduit with a synthetic valve

View Full Paper

Ask AI

Bookmark

Key result

A modified Ross procedure using a synthetic valved conduit resulted in 0% mortality and preserved valvular function with a mean pressure gradient of 11.4 mmHg at 12.6 months.

Why the study?

Does a modified Ross procedure using a synthetic valved conduit provide effective right ventricular outflow tract reconstruction in children and young adults?

Population

11 patients, aged 5 to 22 years, body weight 15.1 to 52.5 kg. Indications for surgery: aortic stenosis…

Design

Case_series

Follow-up

mean 12.6 months

Authors

STShin TakabayashiNiigata University

Discussion

Member takes

Implication

Hypothesis-generating for synthetic conduits in pediatric Ross; larger comparative studies needed before clinical adoption.

Key Points

To evaluate early valvular and right ventricular function in patients undergoing a modified Ross procedure with a synthetic valved conduit for right ventricular outflow tract reconstruction.
Assessed 11 patients aged 5 to 22 years (mean 12.0±4.9 years; weight 15.1–52.5 kg) treated for aortic stenosis, aortic regurgitation, or combined disease.
Performed right ventricular outflow tract reconstruction using hand-fashioned conduits created with a 0.1 mm polytetrafluoroethylene sheet sewn into polytetrafluoroethylene (n=8) or Dacron (n=3) tubes (20–28 mm diameter).
Zero in-hospital or late mortality occurred, and discharge angiocardiography confirmed all artificial valves remained functionally active.
Postoperative mean right atrial pressure and right ventricular end-diastolic pressure showed no statistically significant differences compared with preoperative values.
At a mean follow-up of 12.6 months, echocardiography showed a mean transvalvular pressure gradient of 11.4±11.1 mmHg, with zero patients developing moderate or severe regurgitation.

Study Design

Type

Observational (n=11)

Structured PICO

Does a modified Ross procedure using a synthetic valved conduit provide effective right ventricular outflow tract reconstruction in children and young adults?

Population

11 children and young adults (mean age 12.0 years) with aortic valve disease undergoing a modified Ross procedure, followed for a mean of 12.6 months.

Intervention

Modified Ross procedure for right ventricular outflow tract reconstruction using a hand-fashioned valved conduit prepared by sewing a 0.1 mm thick polytetrafluoroethylene sheet onto the luminal cavity of a 20-28 mm conduit (polytetrafluoroethylene conduit in 8 patients, Dacron graft in 3 patients).

Outcome

Early results of valvular and right ventricular function (including mortality, angiocardiography, right atrial pressure, right ventricular end-diastolic pressure, echocardiographic pressure gradient, and regurgitation)surrogate

A modified Ross procedure using a synthetic valved conduit is a feasible and effective alternative to homografts for right ventricular outflow tract reconstruction in older children.

Cite This Study

Shin Takabayashi (2004) conducted an observational in Aortic stenosis and/or regurgitation (n=11). Modified Ross procedure using a synthetic valved conduit was evaluated on In-hospital or late mortality. A modified Ross procedure using a synthetic valved conduit resulted in 0% mortality and preserved valvular function with a mean pressure gradient of 11.4 mmHg at 12.6 months.

synapsesocial.com/papers/6a96ce4c0f79e4f014b30bd9 https://doi.org/10.1016/j.ejcts.2004.08.029

Topics

Congenital heart disease adults

View Full Paper

Ask AI

Bookmark

Modified Ross procedure using a conduit with a synthetic valve

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Modified Ross procedure using a conduit with a synthetic valve

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider