Key result
Aortic valve replacement using a homograft is an effective option for active endocarditis and complex root destruction, with historical series reporting 82% to 94% survival at 8 years.
Population
Patients requiring aortic valve replacement, particularly for active aortic valve endocarditis with or…
Design
Review
Authors
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Supports homograft use in active endocarditis with root destruction; leaves open durability versus modern alternatives in prospective data.
Aortic homografts remain a valuable surgical option for complex aortic valve replacements, particularly in cases of active endocarditis with root destruction or small aortic roots, though they are subject to progressive regurgitation over time.
Thierry-Pierre Carrel (2009) conducted a review in Aortic valve disease, active aortic valve endocarditis, small aortic root. Aortic valve and/or aortic root replacement using an aortic homograft was evaluated. Aortic valve replacement using a homograft is an effective option for active endocarditis and complex root destruction, with historical series reporting 82% to 94% survival at 8 years.
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