Answers are grounded in this paper and cite their sources.
A study of the micromechanical unzipping of DNA in the framework of the Peyrard-Bishop-Dauxois model is presented. We introduce a Monte Carlo technique that allows accurate determination of the dependence of the unzipping forces on unzipping speed and temperature. Our findings agree quantitatively with experimental results for homogeneous DNA, and for lamda-phage DNA we reproduce the recently obtained experimental force-temperature phase diagram. Finally, we argue that there may be fundamental differences between in vivo and in vitro DNA unzipping.
No takes yet. Share an insight, caveat, or question.
Voulgarakis et al. (2006) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: