Key result
Arterial switch operation for D-TGA resulted in 5.6% in-hospital mortality (3.3% for intact ventricular septum vs 11% for complex D-TGA; P=0.02), with 94% overall survival at 10 years.
Why the study?
Arterial switch operation is the standard of care for neonates with D-TGA, prompting an evaluation of single-centre early and late results.
What are the long-term survival and reintervention rates following the arterial switch operation for D-TGA?
Population
267 patients with D-TGA undergoing ASO
Comparison
D-TGA with intact ventricular septum vs complex D-TGA
Design
Single-centre retrospective cohort study
Follow-up
Median 10.2 years
Authors
Loading...
Supports arterial switch for D-TGA; extends observational survival data but leaves open reintervention needs in complex cases.
Cohort (n=267)
No
What are the long-term survival and reintervention rates following the arterial switch operation for D-TGA?
p-value: p=0.02
The arterial switch operation for D-TGA provides excellent long-term survival (93% at 20 years) and functional capacity, though continuous follow-up is required for reinterventions and coronary anomalies.
Vida et al. (2019) conducted a cohort in D-transposition of the great arteries (D-TGA) (n=267). Arterial switch operation (ASO) was evaluated on In-hospital mortality (p=0.02). Arterial switch operation for D-TGA resulted in 5.6% in-hospital mortality (3.3% for intact ventricular septum vs 11% for complex D-TGA; P=0.02), with 94% overall survival at 10 years.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: