Key result
Among 3,316 patients undergoing elective lung resection for malignancy, 30-day mortality was 1.3%, with respiratory failure (54.5%) and ischemic bowel (22.7%) being the leading causes of death.
Why the study?
Advances in perioperative care may have changed the historical predominance of respiratory failure as the primary cause of mortality following elective lung resection.
What are the main causes of early mortality following elective lung surgery for non-small cell lung cancer?
Design
Retrospective observational study
Follow-up
30 days
Authors
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Alerts clinicians to ischemic bowel as a leading mortality cause after lung resection; leaves open whether preventive strategies improve survival.
Observational (n=3,316)
No
What are the main causes of early mortality following elective lung surgery for non-small cell lung cancer?
While respiratory failure remains the leading cause of mortality after elective lung resection for malignancy, bowel ischemia is a significant and under-recognized second leading cause.
Smelt et al. (2018) conducted an observational in Lung malignancies (NSCLC) (n=3,316). Elective anatomical lung resection was evaluated on 30-day inpatient mortality. Among 3,316 patients undergoing elective lung resection for malignancy, 30-day mortality was 1.3%, with respiratory failure (54.5%) and ischemic bowel (22.7%) being the leading causes of death.
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