Distribution of fibronectin in the maturing, ovulatory and atretic follicles of chicken wasstudied by immunohistochemical methods. In the mature follicles, fibronectin was distributed within the basal lamina, thecal connective tissue and superficial tunic. Fibronectin inthe theca externa distributed along the collagenous bundles. Fibronectin in the thecal tissueof the stigma appeared in the form of fine strands near the time of ovulation and becamefragmented 2h after ovulation. In the atretic follicle, the amount of fibronectin in the thecaltissue was remarkably reduced.From the above findings, it is suggested that fibronectin may participate in the processof disintegration of the thecal connective tissue at the time of ovulation and in atresia.
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Yoshimura et al. (1985) studied this question.