What question did this study set out to answer?

To evaluate the impact of asymptomatic congenital cytomegalovirus (cCMV) infection on neurological status and cognitive, language, and motor development at six months of age.

December 26, 2022The Italian Journal of Pediatrics/Italian journal of pediatricsOpen Access

Early neurodevelopmental outcomes in children with asymptomatic congenital CMV infection

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Authors

MNMaría NovelliNorthwestern University FNFabio NatalePoliclinico Umberto I ANAnna Di NorciaSapienza University of Rome

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Implication

Cohort study reveals mostly normal early outcomes alongside minor motor deficits in infants with asymptomatic congenital cytomegalovirus, suggesting the importance of ongoing developmental...

Key Points

To evaluate the impact of asymptomatic congenital cytomegalovirus (cCMV) infection on neurological status and cognitive, language, and motor development at six months of age.
Followed 56 infants with asymptomatic cCMV infection for 6 months as part of a structured surveillance program.
Assessed neurological outcomes via standard clinical examinations and developmental milestones using Bayley-III Scales.
Early neurological outcomes were generally normal, although a subgroup of infants exhibited minor neurological deficits, specifically muscle tone abnormalities.
Bayley-III scores predominantly remained in the normal range, with 14% of infants scoring below 85 (-1 SD) on the Motor Scale.
Neurological and neurodevelopmental outcomes at 6 months did not differ according to the maternal trimester of infection.

Cite This Study

Novelli et al. (2022) studied this question.

synapsesocial.com/papers/6a96e5fda43071aed1f6be39 https://doi.org/10.1186/s13052-022-01387-3

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December 26, 2022The Italian Journal of Pediatrics/Italian journal of pediatricsOpen Access

Early neurodevelopmental outcomes in children with asymptomatic congenital CMV infection

View Full Paper

Ask AI

Bookmark

Authors

MNMaría NovelliNorthwestern University FNFabio NatalePoliclinico Umberto I ANAnna Di NorciaSapienza University of Rome

Discussion

Member takes

Implication

Cohort study reveals mostly normal early outcomes alongside minor motor deficits in infants with asymptomatic congenital cytomegalovirus, suggesting the importance of ongoing developmental...

Key Points

To evaluate the impact of asymptomatic congenital cytomegalovirus (cCMV) infection on neurological status and cognitive, language, and motor development at six months of age.
Followed 56 infants with asymptomatic cCMV infection for 6 months as part of a structured surveillance program.
Assessed neurological outcomes via standard clinical examinations and developmental milestones using Bayley-III Scales.
Early neurological outcomes were generally normal, although a subgroup of infants exhibited minor neurological deficits, specifically muscle tone abnormalities.
Bayley-III scores predominantly remained in the normal range, with 14% of infants scoring below 85 (-1 SD) on the Motor Scale.
Neurological and neurodevelopmental outcomes at 6 months did not differ according to the maternal trimester of infection.

Cite This Study

Novelli et al. (2022) studied this question.

synapsesocial.com/papers/6a96e5fda43071aed1f6be39 https://doi.org/10.1186/s13052-022-01387-3

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