Key result
Among 7,490 respondents with 808 deaths over 5 years, elevated BMI was associated with lower mortality in men ≥65 years, while hypertension increased mortality risk in women aged 50-64 years.
Why the study?
Do elevated body mass index and hypertension affect general mortality in the Croatian adult population?
Cohort (n=7,490)
Do elevated body mass index and hypertension affect general mortality in the Croatian adult population?
The study confirms the obesity paradox in older men while highlighting the mortality risk of hypertension in middle-aged women, emphasizing the need for primary and secondary prevention.
Hypothesis-generating for age- and sex-specific mortality risks; leaves open causal inference and practice change pending prospective confirmation.
Aim of this study was to investigate association of elevated body mass index and hypertension with general mortality in the cohort from Croatian Adult Health Cohort Study (CroHort). Risk of death according to body mass index (BMI) and blood pressure category, in period 2003/08, was calculated for 7,490 respondents, out of which 6,682 were alive and 808 were dead in 2008. Among men aged 65 and more, elevated BMI was associated with lower risk of death, in accordance with obesity paradox recorded in some previous studies which showed that older men with higher BMI have lower risk of death. Among women aged 50-64 years, being hypertensive was associated with increased risk of death compared to normotensive respondents. Despite obesity paradox which should be further explored, activities on primary and secondary prevention of excess weight and hypertension should be encouraged as means to prevent premature mortality in Croatian population.
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Mihel et al. (2012) conducted a cohort in Elevated body mass index and hypertension (n=7,490). Elevated body mass index and hypertension vs. Normal BMI and normotension was evaluated on General mortality. Among 7,490 respondents with 808 deaths over 5 years, elevated BMI was associated with lower mortality in men ≥65 years, while hypertension increased mortality risk in women aged 50-64 years.
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