Key result
After an arterial switch operation, exercise capacity is reduced (peak oxygen uptake 87.5% of predicted) but left ventricular ejection fraction is preserved (60.7%).
Why the study?
Does the arterial switch operation for transposition of the great arteries result in preserved long-term exercise capacity and left ventricular function compared with healthy controls?
Population
Patients who had undergone an arterial switch operation for transposition of the great arteries with a…
Comparison
Arterial switch operation for transposition of… vs Healthy controls
Design
Meta-analysis
Follow-up
minimum of 6 years
Authors
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Reduced exercise capacity despite preserved LVEF after arterial switch warrants monitoring; confirms LV preservation but challenges assumptions of normal functional recovery.
Meta-Analysis
Does the arterial switch operation for transposition of the great arteries result in preserved long-term exercise capacity and left ventricular function compared with healthy controls?
Long-term follow-up after arterial switch operation for transposition of the great arteries demonstrates preserved left ventricular ejection fraction but reduced exercise capacity.
Wijk et al. (2018) conducted a meta-analysis in Transposition of the great arteries. Arterial switch operation vs. Healthy controls was evaluated on Long-term exercise capacity and left ventricular ejection fraction. After an arterial switch operation, exercise capacity is reduced (peak oxygen uptake 87.5% of predicted) but left ventricular ejection fraction is preserved (60.7%).
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