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Summary: Sera from 72 Papua New Guinean patients with hepatocellular carcinoma were tested for alpha1 fetoprotein, hepatitis B antigen and antibody by sensitive techniques including radio-immunoassay. Alpha1 fetoprotein was detected in 98% of samples and Hepatitis B antigen in 82%. Hepatitis B antibody was present in only 2.8% of samples. The implications of these findings are considered.
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Woodfield et al. (1974) studied this question.
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