Key result
COVID-19 infection can cause severe cardiac manifestations including myocarditis, pericarditis, and myopericarditis, which can be successfully managed with appropriate medical therapy.
Case Report (n=3)
No
Myocarditis, pericarditis, and myopericarditis are potential complications of COVID-19 that can present with or without pneumonia and respond well to standard anti-inflammatory and supportive therapies.
Alerts clinicians to monitor for cardiac complications in COVID-19; leaves open generalizability of management from case reports alone.
COVID-19 has been associated with a variety of cardiac manifestations. Myocarditis and pericarditis have been reported as one of the many cardiac manifestations in association with COVID-19. We describe below three cases of myocarditis, pericarditis with associated pericardial effusion and myopericarditis, respectively, in the setting of COVID-19. Although these entities may occur in isolation, they often occur in association to varying degrees. It could either be the initial diagnosis at the time of presentation or it could occur later in the course of COVID-19 infection. Pericarditis may occasionally be associated with significant pericardial effusion and tamponade requiring therapeutic pericardiocentesis. The assessment of pericardial effusion has been found to be exudative and is usually negative for SARS-CoV-2. Treatment of pericarditis with nonsteroidal anti-inflammatory drugs, colchicine, and corticosteroids has proven to be safe in COVID-19. Myocarditis may present with severe left ventricular systolic dysfunction and cardiogenic shock requiring inotropes and mechanical circulatory support.
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Kumar et al. (2020) conducted a case report in COVID-19 with myocarditis or pericarditis (n=3). COVID-19 was evaluated. COVID-19 infection can cause severe cardiac manifestations including myocarditis, pericarditis, and myopericarditis, which can be successfully managed with appropriate medical therapy.
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