Key result
Surgical correction of atrioventricular septal defect resulted in greater disproportionate left ventricular outflow tract morphometrics, with a greater burden after modified 1-patch repair (P=0.004).
Why the study?
Although a narrow left ventricular outflow tract in atrioventricular septal defect is related to intrinsic morphology, the contribution from the repair technique remains to be quantified.
Does surgical repair impact left ventricular outflow tract morphometrics in patients with atrioventricular septal defect with a common atrioventricular valve orifice?
Cohort (n=152)
Does surgical repair impact left ventricular outflow tract morphometrics in patients with atrioventricular septal defect with a common atrioventricular valve orifice?
p-value: p== .004
Surgical repair of atrioventricular septal defect with a common atrioventricular valve orifice causes immediate postoperative derangements in left ventricular outflow tract morphometrics, particularly with the modified 1-patch technique.
May prompt closer LVOT surveillance after modified 1-patch AVSD repair; leaves open impact on obstruction risk and reintervention.
Objective: Although a narrow left ventricular outflow tract in atrioventricular septal defect is related to its intrinsic morphology, the contribution from the repair technique remains to be quantified. Methods: A total of 108 patients with an atrioventricular septal defect with a common atrioventricular valve orifice were divided into 2 groups: 2-patch (N = 67) and modified 1-patch (N = 41) repair. The left ventricular outflow tract morphometric was analyzed by quantifying the degree of disproportion between subaortic and aortic annular dimensions (disproportionate morphometrics ratio was defined as ≤ 0.9). Z-scores (median, interquartile range) were further analyzed in a subset of 80 patients with immediate preoperative and postoperative echocardiography. A total of 44 subjects with ventricular septal defects served as controls. Results: = .004). Conclusions: Surgical correction resulted in greater disproportionate morphometrics seen immediately postrepair. The impact on the left ventricular outflow tract was observed in all repair techniques, with a greater burden seen after modified 1-patch repair. Video Abstract: This morphometric study in AVSD with common atrio-ventricular valve orifice confirmed further derangements of LV outflow tract morphometrics immediately after surgical repair.
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Chandiramani et al. (2023) conducted a cohort in Atrioventricular septal defect with common atrioventricular valve orifice (n=152). Modified 1-patch repair vs. 2-patch repair was evaluated on Left ventricular outflow tract morphometric (disproportionate morphometrics ratio ≤ 0.9) (p== .004). Surgical correction of atrioventricular septal defect resulted in greater disproportionate left ventricular outflow tract morphometrics, with a greater burden after modified 1-patch repair (P=0.004).
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