interactome profiling of aggregation-prone tau K18-P301L in HEK-Tau-BiFC reporter cells, which revealed eight cellular effectors of tau transmission, including four newly identified ones. ESIPT photochemistry thereby provides a minimally perturbing, self-reporting PAL platform for mapping intracellular interaction networks in their native environment.
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Kozoriz et al. (2026) studied this question.
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