Asymmetric Synthesis of α‐Amino Phosphonates by Using Cinchona Alkaloid‐Based Chiral Phase Transfer Catalyst

A highly enantioselective nucleophilic addition of phosphite esters to imines catalyzed by a chiral phase‐transfer catalyst has been developed. The process affords the hydrophosphonylation of imine products with quaternary stereocenters in good to high yields (up to 95 % yield) and excellent enantioselectivities (up to 99 % ee).