January 1, 2003Sunhwan'giOpen Access

The Prognostic Significance of Statin Therapy According to the Level of C-Reactive Protein in Acute Myocardial Infarction Patients who Underwent Percutaneous Coronary Intervention

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Why the study?

Does statin therapy reduce major adverse cardiac events in acute myocardial infarction patients with elevated CRP undergoing percutaneous coronary intervention?

Population

340 patients with acute myocardial infarction who underwent percutaneous coronary intervention, divided into…

Comparison

Simvastatin 20-40 mg vs No statin therapy

Design

Cohort

Follow-up

1 year

Authors

YHYoung Joon HongInterventional Cardiology MJMyung Ho JeongInterventional Cardiology JLJi Hyun LimChung-Ang University

Discussion

Member takes

Implication

May support statin use in elevated-CRP AMI post-PCI; hypothesis-generating and requires RCT confirmation.

Structured PICO

Does statin therapy reduce major adverse cardiac events in acute myocardial infarction patients with elevated CRP undergoing percutaneous coronary intervention?

Population

340 patients with acute myocardial infarction (AMI) who underwent percutaneous coronary intervention (PCI), divided into normal CRP (<0.5 mg/dL, n=158) and elevated CRP (≥0.5 mg/dL, n=182) groups. Mean age ~59-60 years, ~83% male, based in South Korea.

Intervention

Simvastatin 20-40 mg

Comparator

No statin therapy

Outcome

Major adverse cardiac events (MACE) at 1 yearcomposite

Statin therapy significantly attenuates the increased risk for MACE in AMI patients with elevated CRP levels undergoing PCI.

Cite This Study

Hong et al. (2003) studied this question.

synapsesocial.com/papers/6a970b341f16343146bba125 https://doi.org/10.4070/kcj.2003.33.10.891

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The Prognostic Significance of Statin Therapy According to the Level of C-Reactive Protein in Acute Myocardial Infarction Patients who Underwent Percutaneous Coronary Intervention

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Prognostic Significance of Statin Therapy According to the Level of C-Reactive Protein in Acute Myocardial Infarction Patients who Underwent Percutaneous Coronary Intervention

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider