Cannabinol (CBN) was metabolized in vitro by a 10,000 g supernatant from rat liver. After removal of unchanged CBN and its monohydroxylated metabolites four dihydroxylated metabolites were isolated. By nuclear magnetic resonance and mass spectrometry the compounds were identified as 1'',7-dihydroxy-CBN. Side chain hydroxylation occurred predominantly at C-4'' anc C-3''.
No takes yet. Share an insight, caveat, or question.
Fonseka et al. (1977) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: