Key result
Significant internal carotid artery stenosis (>70%) on preoperative duplex screening, along with advancing age and multi-vessel coronary disease, was associated with post-CABG neurologic events.
Why the study?
The study was conducted to evaluate the use of duplex carotid artery screening in patients undergoing coronary artery bypass graft (CABG).
Does duplex carotid artery screening prior to CABG predict post-CABG stroke in patients with coronary artery disease?
Observational (n=178)
No
Does duplex carotid artery screening prior to CABG predict post-CABG stroke in patients with coronary artery disease?
Significant internal carotid artery stenosis on duplex screening in elderly patients with multi-vessel coronary artery disease or combined risk factors is associated with post-CABG stroke, supporting selective rather than universal screening.
Supports selective carotid screening in high-risk CABG patients; leaves open randomized confirmation of stroke prevention.
OBJECTIVE: To evaluate the use of duplex carotid artery screening in patients undergoing coronary artery bypass graft (CABG). METHODS: This descriptive, observational study was conducted in Radiology Department at King Fahad Military Medical Complex, Dhahran, Kingdom of Saudi Arabia from April 2015-2018. All Saudi patients (n=178) who underwent duplex carotid sonography prior to CABG were retrospectively reviewed for essential morphologic and hemodynamic information to estimate severity of extra-cranial internal carotid artery (ICA) stenosis. Patients with combined CABG and cardiac surgery, and those with limited carotid studies were excluded. Advancing age (65 years or above), gender, smoking, obesity, diabetes (DM), hypertension (HTN), dyslipidemia, coronary vessel disease, cardiac disease and previous stroke were recorded. Post-coronary artery bypass graft neurologic event (namely, transient ischemic attack [TIA] or stroke) was recorded. Chi-square test was used to determine association of stenosis degree with post-CABG neurologic event. RESULTS: One hundred twenty eight patients (72%) were having ICA disease, while significant carotid artery stenosis (>70%) was seen in 11 patients (6.2%). Post-coronary artery bypass graft neurologic event was seen in 4.5% of patients. Advancing age, significant ICA stenosis and multi-vessel coronary disease were seen associated with a post-CABG event. CONCLUSION: Significant ICA stenosis on duplex screening in elderly patients with multi-vessel coronary artery disease or certain risk factors may predict post-CABG stroke.
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Waheed et al. (2019) conducted an observational in Coronary artery disease requiring CABG (n=178). Significant internal carotid artery (ICA) stenosis (>70%) vs. No significant ICA stenosis was evaluated on Post-CABG neurologic event (TIA or stroke). Significant internal carotid artery stenosis (>70%) on preoperative duplex screening, along with advancing age and multi-vessel coronary disease, was associated with post-CABG neurologic events.
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