Key result
Non-obstetric surgery during pregnancy was associated with a higher risk of adverse birth outcomes, including one additional preterm delivery for every 31 operations, though attributable risk was low.
Why the study?
Does non-obstetric surgery during pregnancy increase the risk of adverse birth outcomes in pregnant women?
Population
6,486,280 pregnancies in English NHS hospitals between 2002-3 and 2011-12.
Comparison
Non-obstetric surgery during pregnancy vs Pregnancies in which non-obstetric surgery was…
Design
Cohort
Authors
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May guide counseling on preterm risks with surgery in pregnancy; leaves open causal confirmation in prospective studies.
Observational (n=6,486,280)
Yes
Does non-obstetric surgery during pregnancy increase the risk of adverse birth outcomes in pregnant women?
NNH: 31
Number Needed to Treat: 31
Non-obstetric surgery during pregnancy is associated with a small but statistically significant increased risk of adverse birth outcomes, providing useful reference points for patient counseling.
Aylin et al. (2016) conducted an observational in Pregnancy (n=6,486,280). Non-obstetric surgery vs. No non-obstetric surgery was evaluated on Preterm delivery (NNH 31). Non-obstetric surgery during pregnancy was associated with a higher risk of adverse birth outcomes, including one additional preterm delivery for every 31 operations, though attributable risk was low.
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