Key result
Antithrombin Cambridge II (A384S) is a genetic variant associated with borderline or mildly reduced antithrombin heparin cofactor activity.
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Should not yet change thrombophilia evaluation; hypothesis-generating for mild antithrombin deficiency phenotypes.
To the editor: The antithrombin (AT) Cambridge II (A384S), which results from a nucleotide (nt) G > T substitution at position 13268 of the gene (numbering system from Olds et al[1][1]), is a variant associated with borderline or mildly reduced antithrombin heparin cofactor activity, but normal
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Picard et al. (2007) studied this question. Antithrombin Cambridge II (A384S) is a genetic variant associated with borderline or mildly reduced antithrombin heparin cofactor activity.
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