Key result
Younger age at surgery was associated with an increase in the recovery rate of motor function (0.47%; 95% CI 0.08-0.87; p<0.02) in children with peripheral nerve injuries.
Why the study?
Damage to peripheral nerves significantly impacts patient lives and can lead to disability without timely care, making the determination of prognostic factors affecting outcomes essential.
What are the prognostic factors affecting the recovery of motor function after surgery for peripheral nerve injuries in children?
Meta-Analysis (n=120)
What are the prognostic factors affecting the recovery of motor function after surgery for peripheral nerve injuries in children?
Younger age and more distal level of damage are positive prognostic factors for motor function recovery after surgery for peripheral nerve injuries in children.
Objective. Damage to peripheral nerves has a strong impact on the life of patients, as the absence during the care provided can lead to disability. It is important to determine the prognostic factors that affect the outcome of the disease. Material and methods. During the initial selection, 1902 publications (PubMed) and 675 results were found using the Google Scholar database. From the initially identified search results, an analysis of 5 papers was carried out. Results. The total number of patients with peripheral nerve injuries of the upper extremities was 120. The average age of patients is (9.1 ± 1.5) years old. The conducted meta-analysis of the difference in the average values of recovery of motor function of peripheral nerves after surgery showed: the final increase in the recovery rate of motor function, depending on age, was 0.47 (0.08–0.87) %, p < 0.02; the final increase in the recovery rate of motor function, depending on the level of damage, was 0.71 (0.27–1.13) %, p < 0.02. Conclusion. The obtained results showed the prognostic value of such indicators as age at the time of surgery and the level of damage. Thus, we can confidently say that the smaller the age of the child and the more distal the level of damage, the better results can be expected after surgery.
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Alexandrov et al. (2023) conducted a meta-analysis in peripheral nerve injuries of the upper extremities (n=120). Age at surgery and level of damage was evaluated on recovery rate of motor function depending on age (0.47%, 95% CI 0.08-0.87, p=<0.02). Younger age at surgery was associated with an increase in the recovery rate of motor function (0.47%; 95% CI 0.08-0.87; p<0.02) in children with peripheral nerve injuries.
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