Key result
Intramedullary nailing combined with blocking screws significantly reduced fracture healing time (SMD -2.18) and complications compared to control in patients with lower limb long bone fractures.
Why the study?
Long tubular bone fractures account for about 4% of emergency trauma, with the highest proportion occurring in the lower limb, prompting an assessment of blocking screws for fixation.
Does intramedullary nailing combined with blocking screws improve fracture healing time and reduce complications in individuals with lower limb long bone fractures?
Meta-Analysis (n=1,074)
Does intramedullary nailing combined with blocking screws improve fracture healing time and reduce complications in individuals with lower limb long bone fractures?
Standardized Mean Difference: -2.18 (95% CI -3.17–-1.2)
p-value: p=<0.001
In patients with lower limb long bone fractures, the addition of blocking screws to intramedullary nailing significantly reduces fracture healing time, intraoperative bleeding, and complications, despite prolonging operation time.
Supports adding blocking screws to intramedullary nailing to shorten healing in lower limb fractures; confirms meta-analytic benefit over standard technique.
Background: The incidence of long tubular bone fracture is high, accounting for about 4% of emergency trauma, especially the proportion of long tubular bone (mainly femoral shaft and tibiofibular shaft) in the lower limb is the highest. Methods: To find controlled trials on the effectiveness and side effects of using blocking screws to fixate lengthy bone fractures in the lower leg, the computer searches eight repositories. The examination of the data was carried out utilizing RevMan 5.3 program following a thorough assessment of the overall quality of the research. Results: This investigation eventually comprised 15 papers. Based on the investigation of 15 studies, the fracture healing time was substantially shorter in the test group than that of the control group (SMD: -2.18; 95% Cl: -3.17,-1.20; P<0.001). We revealed no statistically significant differences between the fracture healing rates of comparative groups (OR:1.09; 95% Cl: 0.98,1.20; P=0.098). The operation time of the experimental group was significantly greater than that of the control group (SMD:15.81; 95% Cl: 4.28,27.34; P=0.007). When compared to the control group, the intraoperative bleeding was much less in the experimental group (SMD: -75.60; 95% Cl: -127.93,-23.27; P=0.005). Our investigation showed that the complications of the experimental group were much fewer than those of the contrasted group (OR: 0.51; 95% Cl: 0.31, 0.84; P=0.008). Conclusion: The findings of the present investigation imply that individuals with lower limb long bone fractures (LLLBF) may benefit from intramedullary nailing in conjunction with blocking screws, as evidenced by fracture healing time, fracture healing rate, operation time, intraoperative bleeding, complications, and the above conclusions need to be verified by more high-quality studies.
No takes yet. Share an insight, caveat, or question.
Jin et al. (2023) conducted a meta-analysis in Lower limb long bone fracture (LLLBF) (n=1,074). Intramedullary nails combined with blocking screws vs. Single intramedullary nail or intramedullary nail combined with a steel plate was evaluated on Fracture healing time (SMD -2.18, 95% CI -3.17, -1.20, p=<0.001). Intramedullary nailing combined with blocking screws significantly reduced fracture healing time (SMD -2.18) and complications compared to control in patients with lower limb long bone fractures.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: