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September 1, 2000Journal of Neurology Neurosurgery & PsychiatryOpen Access

Management of intracranial bleeding associated with anticoagulation: balancing the risk of further bleeding against thromboembolism from prosthetic heart valves

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Key result

Anticoagulation with warfarin and heparin in a patient with a prosthetic aortic valve resulted in 3 intracranial bleeds, illustrating the challenge of balancing bleeding and thromboembolic risks.

Population

A patient with a prosthetic aortic valve who sustained an intracranial bleed while taking warfarin, and a…

Design

Case_report

Authors

FCF CrawleyWest Suffolk NHS Foundation Trust

Discussion

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Overview

Underscores individualized anticoagulation decisions after ICH in mechanical valve patients; leaves open optimal regimens for prospective trials.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
1 patient with a prosthetic aortic valve who sustained multiple intracranial bleeds while on anticoagulation.
E
Exposure
Management of anticoagulation (warfarin and heparin) during intracranial haemorrhage

Highlights the clinical dilemma of balancing thromboembolic risk against further bleeding when managing anticoagulation in patients with mechanical heart valves who experience intracranial haemorrhage.

Cite This Study

F Crawley (2000) conducted a case report in Intracranial bleeding associated with anticoagulation for prosthetic heart valves (n=1). Anticoagulation (warfarin and heparin) was evaluated. Anticoagulation with warfarin and heparin in a patient with a prosthetic aortic valve resulted in 3 intracranial bleeds, illustrating the challenge of balancing bleeding and thromboembolic risks.

synapsesocial.com/papers/6a972040f69cd3f692022ea2https://doi.org/10.1136/jnnp.69.3.396
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Thromboembolic and bleeding complications in patients with mechanical heart valve prostheses.1994 · 1,068 citations
  2. 2Emergency reversal of anticoagulation after intracerebral hemorrhage.1992 · 298 citations
  3. 3Emergency Oral Anticoagulant Reversal: The Relative Efficacy of Infusions of Fresh Frozen Plasma and Clotting Factor Concentrate on Correction of the Coagulopathy1997 · 407 citations
  4. 4Prosthetic Heart Valves1996 · 812 citations
  5. 5Oral Anticoagulants and Intracranial Hemorrhage1995 · 543 citations