Key result
In pacemaker-dependent subjects, an optimized sensor setting did not increase maximal workload (133 W vs 129 W) or augment cardiac output compared to a default setting.
Why the study?
Does an optimized pacemaker sensor setting improve cardiac output and cerebral blood velocity during exercise in pacemaker-dependent subjects?
Population
Pacemaker-dependent subjects with complete heart block and preserved myocardial function
Comparison
Pacemaker set to 'optimized' sensor setting… vs Pacemaker set to 'default' sensor setting during…
Authors
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No benefit on workload or cardiac output with optimized settings; leaves open effects on cerebral perfusion in pacemaker-dependent patients.
Does an optimized pacemaker sensor setting improve cardiac output and cerebral blood velocity during exercise in pacemaker-dependent subjects?
Absolute Event Rate: 133% vs 129%
In pacemaker-dependent patients with complete heart block, a more aggressive rate-responsive pacing setting during exercise does not improve cardiac output or cerebral perfusion compared to default settings.
Bogert et al. (2005) studied Pacemaker-dependent with complete heart block. Optimized sensor setting (OSS) vs. Default sensor setting (DSS) was evaluated on Maximal workload. In pacemaker-dependent subjects, an optimized sensor setting did not increase maximal workload (133 W vs 129 W) or augment cardiac output compared to a default setting.
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