Key result
Minimally invasive aortic valve replacement resulted in similar intrahospital mortality compared to conventional sternotomy, while reducing hospital stay despite longer cardiopulmonary bypass times.
Why the study?
Minimally invasive aortic valve replacement has been increasingly used to reduce trauma and accelerate recovery, prompting a comparison of perioperative outcomes and early mortality against standard medial sternotomy.
Does minimally invasive aortic valve replacement improve perioperative outcomes and early mortality compared to medial sternotomy in patients undergoing isolated aortic valve replacement?
RCT (n=70)
Open-label
Randomized
No
Does minimally invasive aortic valve replacement improve perioperative outcomes and early mortality compared to medial sternotomy in patients undergoing isolated aortic valve replacement?
Minimally invasive aortic valve replacement is a safe alternative to conventional sternotomy, offering shorter hospital stays despite longer cardiopulmonary bypass times.
Supports minimally invasive AVR as safe alternative shortening hospital stay; confirms safety in this RCT.
Standard surgical approach in an aortic valve treatment is medial sternotomy.In recent years minimally invasive procedures have been used more toward decrease of trauma and faster recovery of patients.The aim of our study is a comparison of the preoperative, perioperative results and early mortality of patients in whom aortic valve replaced through mini-(Mini-AVR) or medialsternotomy.The study included 70 patients.Preoperative, intraoperative and early postoperative patients, and characteristics were analysed.Preoperative variables were homogenous.The euroscore value was significantly higher in medial sternotomy group (p = 0.037).The cross-clamp and cardiopulmonary bypass time were longer in mini-AVR group (p < 0.001).There was no difference in the incidence of postoperative myocardial infarction, stroke and acute renal failure.One patient in each group underwent surgical revision because of bleeding.There was no difference in hospital mortality between two groups.Postoperative blood loss was insignificantly lower in mini-AVR group (p = 0.69).Three patients had suffered from wound infection after medial sternotomy: 2 superficial infections and 1 deep infection (p = 0.4).The length of intensive care unit was similar in both groups.Patient in mini-AVR group had shorter hospital stay when compared with patient operated thought medial sternotomy (8 days (IQR 7-11) vs 7 days (IQR 7-9)).The mini-AVR reduces tissue trauma and hospital stay and also promotes a patient's recovery.In high-risk patients with comorbidities like obesity, diabetes and elder patients reduces the prevalence of infection.
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Živković et al. (2019) conducted an RCT in Isolated aortic valve replacement (n=70). Minimally invasive aortic valve replacement (mini-AVR) vs. Conventional aortic valve replacement through medial sternotomy was evaluated on Intrahospital mortality (p=1.0). Minimally invasive aortic valve replacement resulted in similar intrahospital mortality compared to conventional sternotomy, while reducing hospital stay despite longer cardiopulmonary bypass times.
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