Key result
Ministernotomy for aortic valve replacement significantly reduced median postoperative drainage (360 ml vs 590 ml, p<0.001) and shortened hospital stay compared to conventional sternotomy.
Why the study?
Does ministernotomy compared to conventional sternotomy improve peri- and post-operative outcomes in patients undergoing isolated aortic valve replacement?
Cohort (n=150)
No
Does ministernotomy compared to conventional sternotomy improve peri- and post-operative outcomes in patients undergoing isolated aortic valve replacement?
Ministernotomy for isolated aortic valve replacement is a safe alternative to full sternotomy that reduces postoperative blood loss, mechanical ventilation time, and hospital stay without increasing morbidity or mortality.
Supports ministernotomy as alternative for isolated AVR; leaves open confirmation in randomized trials.
Introduction: Aortic valve replacement (AVR) is the gold standard in treating symptomatic aortic valve defects. To improve the healing process and limit the trauma, the minimally invasive approach was introduced. Aim: To compare the peri-and post-operative results of aortic valve replacement performed via conventional full sternotomy (con-AVR) and of AVR performed via partial upper sternotomy (mini-AVR). Material and methods: The total study population was divided into 2 demographically homogeneous groups: mini-AVR (n = 74) and con-AVR (n = 76). There were no statistically significant differences in preoperative echocardiography. Results: Aortic cross-clamp time and cardiopulmonary bypass time were significantly longer in the mini-AVR group. Shorter mechanical ventilation time, hospital stay and lower postoperative drainage were observed in the mini-AVR group (p < 0.05). Biological prostheses were more frequently implanted in the mini-AVR group (p < 0.05). Patients from the mini-AVR group reported less postoperative pain. No significant differences were found in the diameter of the implanted aortic prosthesis, the amount of inotropic agents and painkillers, postoperative left ventricular ejection fraction (LVEF), medium and maximum transvalvular gradient or the number of transfused blood units. There were no differences in the frequency of postoperative complications such as mortality, stroke, atrial fibrillation, renal failure, wound infection, sternal instability, or the need for rethoracotomy. Conclusions: Ministernotomy for AVR is a safe method and does not increase morbidity and mortality. It significantly reduces post-operative blood loss and shortens hospital stay. Ministernotomy can be successfully used as an alternative method to sternotomy.
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Filip et al. (2018) conducted a cohort in Isolated aortic valve malformation (n=150). Ministernotomy (mini-AVR) vs. Conventional full sternotomy (con-AVR) was evaluated on Postoperative drainage (ml) (p=<0.001). Ministernotomy for aortic valve replacement significantly reduced median postoperative drainage (360 ml vs 590 ml, p<0.001) and shortened hospital stay compared to conventional sternotomy.
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