What is the clinical evidence from this study?

Study design: Meta-Analysis. Population: Coronary heart disease with anxiety and depression (n=771). Intervention: Exercise therapy vs. Standard medical care or non-exercise intervention. Primary outcome: Anxiety symptoms (SMD -0.61, 95% CI -0.86, -0.35).

October 11, 2021Frontiers in Cardiovascular MedicineOpen Access

Effects of Exercise Therapy on Anxiety and Depression in Patients With Coronary Heart Disease: A Meta-Analysis of a Randomized Controlled Study

View Full Paper

Ask AI

Bookmark

Key result

Exercise therapy significantly improved anxiety (SMD -0.61) and depression (SMD -0.48) symptoms compared to control interventions in patients with coronary heart disease.

Why the study?

The study was conducted to evaluate the effect of exercise therapy on anxiety and depression symptoms in patients with coronary heart disease.

Does exercise therapy improve anxiety and depression in patients with coronary heart disease?

Population

771 subjects across 11 randomized clinical studies

Comparison

Exercise therapy vs control

Design

Systematic review and meta-analysis of randomized clinical studies

Authors

LWLina WangSouth China Agricultural University JZJie ZhanGuangzhou University of Chinese Medicine ZWZhiyuan WuHarvard University

Discussion

Member takes

Implication

Supports integrating exercise therapy into cardiac rehabilitation for CHD; confirms mental health benefits in meta-analysis.

Study Design

Type

Meta-Analysis (n=771)

Structured PICO

Does exercise therapy improve anxiety and depression in patients with coronary heart disease?

Population

771 adults with coronary heart disease and elevated levels of anxiety or depression across 11 randomized controlled trials, with interventions lasting 10 days to 24 weeks.

Intervention

Exercise therapy alone or as part of a comprehensive cardiac rehabilitation program (including aerobic, strength, balance training, deep breathing, or inspiratory muscle training) for 10 days to 24 weeks.

Comparator

Standard medical care or non-exercise intervention (such as psychological education, antidepressant drugs, or stress management).

Outcome

Depression and anxiety severity assessed by validated self-reporting tools (e.g., HADS, GAD-7, HAMA, DASS, HAMD, SDS, PHQ-9, BDI, CDS).patient reported

Main Result

Standardized Mean Difference: -0.61 (95% CI -0.86–-0.35)

Exercise therapy significantly alleviates anxiety and depression symptoms in patients with coronary heart disease, supporting its integration into cardiac rehabilitation programs.

Limitations

High statistical heterogeneity in the combined results for depression
Majority of participants were male, limiting generalizability to women
Many different anxiety and depression scales were used across the included trials
Some studies included exercise as part of a multicomponent intervention, making it difficult to isolate the effect of exercise alone
Methodological weaknesses in some included studies, such as lack of blinding
Methodological weaknesses in included studies (insufficient reporting of allocation concealment, blinding, and selective reporting)
Small number of studies reporting secondary outcomes (peak oxygen concentration and 6-min walk test)

Cite This Study

Wang et al. (2021) conducted a meta-analysis in Coronary heart disease with anxiety and depression (n=771). Exercise therapy vs. Standard medical care or non-exercise intervention was evaluated on Anxiety symptoms (SMD -0.61, 95% CI -0.86, -0.35). Exercise therapy significantly improved anxiety (SMD -0.61) and depression (SMD -0.48) symptoms compared to control interventions in patients with coronary heart disease.

synapsesocial.com/papers/6a972a4f570fc54467ccd03e https://doi.org/10.3389/fcvm.2021.730155

View Full Paper

Ask AI

Bookmark

Effects of Exercise Therapy on Anxiety and Depression in Patients With Coronary Heart Disease: A Meta-Analysis of a Randomized Controlled Study

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Effects of Exercise Therapy on Anxiety and Depression in Patients With Coronary Heart Disease: A Meta-Analysis of a Randomized Controlled Study

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Also Consider