Answers are grounded in this paper and cite their sources.
Oxidative heterocoupling between two Grignard reagents RMgX and R′MgX is made possible by manganese catalysis with O2 as an oxidant. This procedure, development of which was based on mechanistic analysis of the corresponding homocoupling reaction, can be steered towards the heterocoupling product at the expense of the homocoupling products by judicious choice of the R and R′ groups (see examples).
No takes yet. Share an insight, caveat, or question.
Cahiez et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: