Key result
Older age in patients undergoing coronary artery bypass grafting was associated with significantly lower postoperative cognitive performance on the Mini Mental State examination (P<0.025).
Why the study?
Does older age increase the risk of postoperative psychiatric symptoms and cognitive dysfunction in patients undergoing coronary artery bypass grafting?
Case-Control
Does older age increase the risk of postoperative psychiatric symptoms and cognitive dysfunction in patients undergoing coronary artery bypass grafting?
p-value: p=<0.025
Older patients undergoing CABG are at increased risk for postoperative cognitive dysfunction compared to younger patients.
May warrant enhanced cognitive surveillance in older CABG patients; extends prior associations but requires prospective confirmation.
Coronary artery bypass grafting in older patients usually results in a favorable surgical outcome. To assess whether age confers greater risk for postoperative psychiatric symptoms in these patients, we retrospectively examined 58 cases (mean age 62.5 years) comparing pertinent clinical features of the index patients to matched controls (mean age 51.7 years). Analysis of the data, including scores on preoperative and postoperative scales measuring anxiety, depression, and cognitive function, showed a statistically significant difference in the cognitive performance of the elderly as shown by lower scores on the Mini Mental State examination (chi-square, P less than .025). Our findings support future efforts to address the clinical relevance of cognitive dysfunction in older coronary bypass patients.
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Folks et al. (1986) conducted a case-control in Coronary artery bypass grafting. Older age vs. Younger age (matched controls) was evaluated on Cognitive performance on the Mini Mental State examination (p=<0.025). Older age in patients undergoing coronary artery bypass grafting was associated with significantly lower postoperative cognitive performance on the Mini Mental State examination (P<0.025).
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