Enantiomeric separation of racemic phenglutarimide (PG) by chiral high performance liquid chromatography is reported using cellulose tris (3,5-dimethylphenyl carbamate) known as Chiralcel OD chiral stationary phase. Maximum resolution (Rs) of 1.26 is obtained for the enantiomers of PG. The method could be applied for preparative scale chromatography and in the assay of PG in biological fluids.
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Aboul‐Enein et al. (1994) studied this question.
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