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Rabbit lenses were made cataractous by incubating in culture medium with added tyrosine and tyrosinase. The content of GSH was drastically lowered in the cataractous lens. The GSH which was lost from the lens could be partially recovered as GSSG in the medium. This finding may explain the fate of lens GSH, both normally and in cataract formation.
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Srivastava et al. (1968) studied this question.
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