Key result
The i-STAT system provided ACT measurements with a mean difference of 24 +/- 101 s compared to the Hemochron system, and both correlated significantly with heparin levels (P < 0.001).
Why the study?
Does the i-STAT system provide comparable ACT measurements to the Hemochron system and correlate with heparin levels in patients undergoing cardiopulmonary bypass or hemodialysis?
Observational (n=29)
Does the i-STAT system provide comparable ACT measurements to the Hemochron system and correlate with heparin levels in patients undergoing cardiopulmonary bypass or hemodialysis?
Mean Difference: 24
p-value: p=<0.001
The i-STAT system provides ACT measurements comparable to the traditional Hemochron system and correlates well with heparin levels during cardiopulmonary bypass and hemodialysis.
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May support i-STAT as Hemochron alternative for ACT; leaves open prospective validation before practice change.
Paniccia et al. (2003) conducted an observational in Patients undergoing cardiopulmonary bypass or hemodialysis (n=29). i-STAT system vs. Hemochron system was evaluated on Mean difference between ACT methods and correlation with heparin levels (MD 24 s, p=<0.001). The i-STAT system provided ACT measurements with a mean difference of 24 +/- 101 s compared to the Hemochron system, and both correlated significantly with heparin levels (P < 0.001).
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