Key result
Routine administration of low-molecular-weight heparin suggests a reduction in deep venous thrombosis rates after non-large-joint surgeries, though further clinical studies are needed.
Why the study?
Does routine administration of low-molecular-weight heparin reduce the rate of deep venous thrombosis in patients undergoing non-large-joint surgeries?
Does routine administration of low-molecular-weight heparin reduce the rate of deep venous thrombosis in patients undergoing non-large-joint surgeries?
Thromboprophylaxis with low-molecular-weight heparin may reduce deep venous thrombosis in high-risk patients undergoing non-large-joint orthopedic procedures, but more data is needed to establish risk-benefit and cost-effectiveness.
The risk of venous thromboembolism, particularly deep venous thrombosis, after knee arthroscopy, surgically assisted arthroscopy, or treatment of lower extremity fracture may be substantial in patients with factors known to increase the risk of postoperative thromboembolism. Few prospective studies have examined the effect of prophylaxis in these patient populations. However, results suggest that routine administration of a low-molecular-weight heparin reduces the rate of deep venous thrombosis in such patients. Additional clinical studies are necessary to determine whether the benefits of prophylaxis outweigh its risks and whether it is cost-effective. Until such data are available, risk for deep venous thrombosis must be assessed in all patients undergoing an orthopedic procedure. Thromboprophylaxis with pharmacologic agents may be considered in those at high risk.
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James E. Muntz (2003) conducted a review in Venous thromboembolism in non-large-joint surgeries. Low-molecular-weight heparin was evaluated on Deep venous thrombosis. Routine administration of low-molecular-weight heparin suggests a reduction in deep venous thrombosis rates after non-large-joint surgeries, though further clinical studies are needed.
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