The enantioselective syntheses of (+)-lyconadin A and (−)-lyconadin B are described. Key bond constructions include a strategy-level intramolecular aldol/conjugate addition cascade, an olefin aminoiodination, and a novel one-pot α-pyridinone annulation.
No takes yet. Share an insight, caveat, or question.
Beshore et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: