Key result
Intravenous administration of 20% lipid emulsion rapidly reversed central nervous system toxicity and restored consciousness within 30 seconds following inadvertent intravenous bupivacaine injection.
Population
18-year-old primigravida, weighing 86 kg, at 38 weeks gestation, presenting for induction of labor with…
Design
Case_report
Follow-up
4 days postoperative
Authors
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May support lipid emulsion in bupivacaine CNS toxicity; hypothesis-generating case report requiring prospective validation before practice change.
Case Report (n=1)
No
Intravenous lipid emulsion may rapidly reverse central nervous system toxicity caused by inadvertent intravenous bupivacaine injection.
Andrew G. Spence (2007) conducted a case report in Bupivacaine-induced central nervous system toxicity (n=1). Intravenous lipid emulsion (20% Intralipid) was evaluated on Recovery of consciousness. Intravenous administration of 20% lipid emulsion rapidly reversed central nervous system toxicity and restored consciousness within 30 seconds following inadvertent intravenous bupivacaine injection.
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