Key result
This review highlights the role of zinc in the cardiovascular system, including its involvement in heart failure, vascular calcification, and myocardial infarction.
This review summarizes the role of zinc in cardiovascular pathology, including heart failure, vascular calcification, and myocardial infarction, particularly in high-risk populations with chronic kidney disease and type II diabetes.
May warrant zinc assessment in CKD and diabetes; leaves open therapeutic effects without interventional trials.
Zinc is an essential trace element due to its role as a key part of human enzymatic activity. As a cofactor in metalloenzymes and metalloproteins, zinc participates in diverse biological functions, including gene transcription, translation, and replication, phagocytosis, and immunoglobulin and cytokine production. In this review, we will focus on the role of zinc in the cardiovascular system, including heart failure, vascular calcification, and myocardial infarction. We will further highlight the role of zinc in cardiovascular pathology in individuals with chronic kidney disease, and type II diabetes mellitus, groups uniquely at risk for cardiovascular morbidity and mortality.
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A 2022 study conducted a review in Cardiovascular disease. Zinc was evaluated. This review highlights the role of zinc in the cardiovascular system, including its involvement in heart failure, vascular calcification, and myocardial infarction.