Key result
The pumping oxygenator prototypes achieved blood flow rates up to 1,250 ml/min and physiological oxygen transfer at flow rates < 900 ml/min, confirming the feasibility of integrating oxygenation and pulsatile pumping.
Population
Two small-sized (1 m2 exchange surface area) pumping oxygenator prototypes for in vitro testing
Design
Preclinical
Authors
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Supports preclinical development of integrated devices; leaves open human translation pending further testing.
In vitro testing of a novel pumping oxygenator demonstrated the feasibility of integrating pulsatile pumping and blood oxygenation in a single device.
Fiore et al. (2000) studied this question. Pumping oxygenator was evaluated on Blood flow rates and gas transfer (VO2, VCO2). The pumping oxygenator prototypes achieved blood flow rates up to 1,250 ml/min and physiological oxygen transfer at flow rates < 900 ml/min, confirming the feasibility of integrating oxygenation and pulsatile pumping.
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