Key result
In 9 test conditions at 4 L/min flow, membrane oxygenators slightly affected pulsatility, whereas the arterial pipe line caused large damping and head losses.
Population
Mechanical mock-up system simulating physiologic vascular impedance
Design
Preclinical
Authors
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May warrant shorter arterial tubing to minimize damping in pulsatile CPB; hypothesis-generating pending human validation.
Arterial pipe lines in extracorporeal circuits are responsible for significant damping of pulsatile flow, suggesting that shorter lines are needed to optimize pulsatile cardiopulmonary bypass.
Inzoli et al. (1997) studied Cardiopulmonary bypass (simulated). Membrane oxygenators and extracorporeal circuits was evaluated on Pressure drops and inflow-outflow differences across the components of the arterial line. In 9 test conditions at 4 L/min flow, membrane oxygenators slightly affected pulsatility, whereas the arterial pipe line caused large damping and head losses.
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