Why the study?
Does high systolic blood pressure increase the risk of total and cardiovascular mortality in 80-year-old Japanese adults?
Population
639 community-dwelling adults aged exactly 80 years old, from Fukuoka Prefecture, Japan.
Comparison
Systolic blood pressure ≥160 mmHg or 140-159 mmHg vs Systolic blood pressure <140 mmHg (Group 1)
Design
Cohort
Follow-up
4 years
Key result
In 80-year-old Japanese adults, systolic blood pressure over 160 mmHg was not significantly associated with total mortality compared to below 140 mmHg (RR 1.71, p=0.35).
Authors
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High SBP not linked to mortality in this octogenarian cohort; leaves open optimal targets and should not yet change practice.
Cohort (n=639)
Yes
Does high systolic blood pressure increase the risk of total and cardiovascular mortality in 80-year-old Japanese adults?
Relative Risk: 1.71 (95% CI 0.81–3.58)
p-value: p=0.35
While high systolic blood pressure was not associated with increased mortality in the general 80-year-old population, it significantly increased mortality risk in those with pre-existing cardiovascular disease or those taking antihypertensive medications.
Kagiyama et al. (2008) conducted a cohort in General population (very elderly) (n=639). Systolic blood pressure ≥160 mmHg vs. Systolic blood pressure <140 mmHg was evaluated on Total mortality (RR 1.71, 95% CI 0.81-3.58, p=0.35). In 80-year-old Japanese adults, systolic blood pressure over 160 mmHg was not significantly associated with total mortality compared to below 140 mmHg (RR 1.71, p=0.35).