Key result
Obesity, diabetes mellitus, COPD, preoperative stay >1 week, pulmonary hypertension, perioperative MI, and reoperation were identified as independent risk factors for post-surgical mediastinitis.
Why the study?
What are the independent risk factors associated with the development of post-surgical mediastinitis in patients undergoing cardiovascular surgery?
Case-Control (n=489)
What are the independent risk factors associated with the development of post-surgical mediastinitis in patients undergoing cardiovascular surgery?
Obesity, diabetes, COPD, prolonged preoperative stay, pulmonary hypertension, perioperative MI, and reoperation are independent risk factors for mediastinitis after cardiovascular surgery.
Answers are grounded in this paper and cite their sources.
May inform targeted surveillance in cardiac surgery; leaves open prospective validation before changing practice.
We report results of a case-control study in which we evaluated 41 risk factors potentially associated with the development of post-surgical mediastinitis. There were 163 case patients and 326 control patients. Independent risk factors kept in the final multivariate logistic regression model were obesity (defined as a body mass index of greater than 30), diabetes mellitus, chronic obstructive pulmonary disease, preoperative stay longer than 1 week, pulmonary hypertension, perioperative myocardial infarction, and reoperation.
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Gude et al. (2006) conducted a case-control in Post-surgical mediastinitis after cardiovascular surgery (n=489). Multiple risk factors (obesity, diabetes, COPD, prolonged preoperative stay, pulmonary hypertension, perioperative MI, reoperation) vs. Control patients without mediastinitis was evaluated on Development of post-surgical mediastinitis. Obesity, diabetes mellitus, COPD, preoperative stay >1 week, pulmonary hypertension, perioperative MI, and reoperation were identified as independent risk factors for post-surgical mediastinitis.
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