Key result
Obesity, diabetes mellitus, COPD, preoperative stay >1 week, pulmonary hypertension, perioperative MI, and reoperation were independent risk factors for postsurgical mediastinitis.
Case-Control (n=489)
Patient comorbidities and perioperative factors such as obesity, diabetes, and reoperation independently increase the risk of mediastinitis following cardiovascular surgery.
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May aid preoperative risk stratification in cardiac surgery; leaves open prospective validation of prevention strategies.
We report results of a case-control study in which we evaluated 41 risk factors potentially associated with the development of postsurgical mediastinitis. There were 163 case patients and 326 control patients. Independent risk factors kept in the final multivariate logistic regression model were obesity (defined as a body mass index of greater than 30), diabetes mellitus, chronic obstructive pulmonary disease, preoperative stay longer than 1 week, pulmonary hypertension, perioperative myocardial infarction, and reoperation.
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Gude et al. (2006) conducted a case-control in Postsurgical mediastinitis after cardiovascular surgery (n=489). Risk factors (obesity, diabetes mellitus, COPD, preoperative stay >1 week, pulmonary hypertension, perioperative MI, reoperation) vs. Absence of risk factors was evaluated on Development of postsurgical mediastinitis. Obesity, diabetes mellitus, COPD, preoperative stay >1 week, pulmonary hypertension, perioperative MI, and reoperation were independent risk factors for postsurgical mediastinitis.
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