Racemization wanted: The dynamic kinetic resolution of secondary alcohols can be achieved by a simple and readily available catalyst system. Substrate racemization is effected at room temperature by a combination of (racemic) 1,1′-bi-2-naphthol (binol) or 2,2′-biphenol with AlMe3, and a lipase performs enantiospecific acylation (see scheme).
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Berkessel et al. (2006) studied this question.
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