The occurrence of blood group reactive substances in some species of marine invertebrates is reported. These include: 1. Antigens on the hemerythrocytes of the sipunculid, Dendrostomum zostericolum, that react with various antiserums including human anti-A, human anti-B and anti-Forssman, and a comparison of these reactions with those of the hemocytes of the inn-keeper worm, Urechis caupo. 2. A substance in the serum of the spiny lobster, Panulirus interruptus, that agglutinates erythrocytes carrying the Ju2 antigen in whale species. These include the sperm, humpback, sei and finback whales. 3. A substance in Octopus bimaculatus serum that specifically inhibits the agglutination by anti-A serum of human cells carrying the A1 and A2 antigens.
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Cushing et al. (1963) studied this question.