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Alkaloids alchemy: A synthesis of the Lycopodium alkaloid (+)-fawcettidine (see structure) has been developed which requires 16 steps from (R)-(+)-pulegone as the chiral starting material. Key steps include a platinum(II)-catalyzed annulation reaction of a functionalized enamide and a one-pot Ramberg–Bäcklund process.
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Kozak et al. (2008) studied this question.
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