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Small rings: Only a few methods are known for the synthesis of cyclopropane carbaldehydes and cyclopropyl ketones 2. In a new, simple route to highly enantioenriched trisubstituted three-membered rings, 4-hydroxy-1-alkenyl N,N-diisopropyl carbamates 1 are treated with NaH, resulting in migration of the carbamoyl group and intramolecular enolate alkylation.
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Kalkofen et al. (2004) studied this question.
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