HL‐A Antibodies and Cold Lymphocytotoxins

Thirty sera with anti‐HL‐A antibodies were studied at +15°C to find out whether cold lymphocytotoxins were, in fact, not anti‐HL‐A antibodies. Two conclusions were drawn from this research: firstly, that anti‐HL‐A were revealed at +15°C and that the HL‐A specificity was often broader at +15°C than at +37°C. Secondly, that some sera, with a well defined +37°C anti‐HL‐A specificity, showed at +15°C a combination of anti‐HL‐A antibodies and cold lymphocytotoxic antibodies which could be dissociated by absorption on platelets.