Key result
A galactolipid isolated from rose hip (Rosa canina) inhibited the chemotaxis of human peripheral blood neutrophils in vitro without toxicity.
Why the study?
Does a galactolipid from Rosa canina inhibit chemotaxis of human peripheral blood neutrophils in vitro?
Population
Human peripheral blood neutrophils in vitro
Design
Preclinical
Authors
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In vitro neutrophil chemotaxis inhibition by rose hip galactolipid is hypothesis-generating; leaves open any clinical anti-inflammatory role pending in vivo data.
Does a galactolipid from Rosa canina inhibit chemotaxis of human peripheral blood neutrophils in vitro?
A specific galactolipid from rose hips inhibits human neutrophil chemotaxis in vitro without toxicity, potentially explaining the anti-inflammatory properties of rose hip herbal remedies.
Larsen et al. (2003) studied this question. Galactolipid (2S)-1,2-di-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3-O-beta-d-galactopyranosyl glycerol (1) from Rosa canina was evaluated on Chemotaxis of human peripheral blood neutrophils in vitro. A galactolipid isolated from rose hip (Rosa canina) inhibited the chemotaxis of human peripheral blood neutrophils in vitro without toxicity.
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